Molecular Genetics

Molecular genetics is the branch of phylogeny that analyses hereditary molecular differences, mainly in DNA sequences, to gain information on an organism's evolutionary relationships. The result of a molecular genetic analysis is expressed in a genetic tree. Molecular genetics are important for addressing various biological questions such as relationships among species or genes, the origin and spread of viral infection and the demographic changes and migration patterns of species. Molecular genetics have permeated nearly every branch of biology, and the plethora of phylogenetic methods and software packages that are now available may seem daunting to an experimental biologist. Here, we review the major methods of molecular genetic analysis, including parsimony, distance, likelihood and Bayesian methods.

The term molecular genetics sometimes refers to a fundamental theory alleging that genes direct all life processes through the production of polypeptides, sometimes to a more modest basic theory about the expression and regulation of genes at the molecular level, and sometimes to an investigative approach applied throughout biomedical science that is based on investigative strategies grounded in the basic theory about genes.

 

  • Gene Flow
  • Phylogeny as hypothesis
  • Inbreeding
  • Genetic drift
  • Population genetics
  • Genetic Epidemiology of Infectious diseases

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